Dr. Timothy C. Hall

Distinguished Professor of Biology

Director, Institute of Developmental and Molecular Biology


Office Address:
Texas A&M University
BSBW 407
3258 TAMU
College Station, TX

Labs: BSBW 401 and 435

Phone: 979-845-7728

Fax: 979-862-4098

Email: tim@idmb.tamu.edu

URL: Hall Lab



University of Nottingham, U.K., B.Sc., Class I (Hons), 1962, Botany

University of Nottingham, U.K., PhD., 1965, Botany, Plant Physiology

University of Minnesota, St. Paul, Postdoctoral, 1965-66, Horticulture, Plant Physiology




My lab studies the basis of gene regulation in plants, especially the involvement of chromatin in spatial control of expression and in gene silencing.




1966 - 1982 - Assistant, Associate (1970) and Full Professor (1975), University of Wisconsin-Madison, Dept. of Horticulture (on leave of absence 1981-82)

1982 - 1984 - Adjunct Professor of Biophysics and Genetics, University of Wisconsin-Madison

1984 - present - Distinguished Professor of Biology, Texas A&M University




Hall, T. C., Chandrasekharan, M. B. and Li, G. 1999. Phaseolin: its past, properties, regulation and future. In: Seed Proteins. Casey, R. and Shewry, P. R., eds. Kluwer, Dordrecht, The Netherlands. pp. 209-240.

Kumpatla, S. P. and Hall, T. C. 1999. Sequence rearrangements, repeats and extensive methylation in a multicopy silencing-prone transgene locus in rice. IUBMB-Life, 48: 459-467.

Li, G., Bishop, K. J., Chandrasekharan, M. B. and Hall, T. C. 1999. ß-phaseolin gene activation is a two-step process: PvAlf-facilitated chromatin modification followed by abscisic acid-mediated gene activation. Proc. Natl. Acad. Sci., U.S.A. 96: 7104-7109.

Li, G. and Hall, T. C. 1999. Footprinting in vivo reveals changing profiles of multiple factor interactions with the ß-phaseolin promoter during embryogenesis. Plant J. 18: 633-642.

Iyer, L.M., Kumpatla, S.P., Chandrasekharan, M.B. Hall, T.C. 2000. Transgene silencing in monocots. Plant Mol. Biol. 43: 323-346.

Kharb, P., Dong, J., Islam-Faridi, M.N., Stelly, D. M. and Hall, T. C. 2000. Fluorescence in situ hybridization of single copy transgenes in rice chromosomes. In Vitro Cell. Dev. Biol. - Plant 37: 1-5.

Dong, J., Kharb, P., Cervera, M., and Hall, T.C. 2001. The use of FISH in chromosomal localization of transgenes in rice. Invited paper, for a special issue on Chromosome Painting in Methods in Cell Science 23: 105-113.

Dong, J., Kharb, P., Teng, W. and Hall, T.C. 2001. Characterization of rice transformed via an Agrobacterium-mediated inflorescence transformation. Mol. Breeding 7:187-194.

Hall, T. C., Kumpatla, S. P., Kharb, P., Iyer, L., Cervera, M., Jiang, Y., Wang, T., Yang, G., Teerawanichpan, P. Narangajavana, J. and Dong, J. 2001. Gene silencing and its reactivation in transgenic rice. p. 465-481. In: Rice Genetics IV (G. S. Khush, D. S. Brar and B. Hardy eds) Science Publishers, Inc., New Delhi (India) and International Rice Research Institute, Los Baños (Philippines).

Li, G., Bishop, K.J. and Hall, T.C. 2001. De novo activation of the ß-phaseolin promoter by phosphatase or protein synthesis inhibitors. J. Biol. Chem. 276: 2062-2068.

Li, G., Chandrasekharan, M.B., Wolffe, A.P. and Hall, T.C. 2001. Chromatin structure and phaseolin gene regulation. Plant Mol. Biol. 46:121-129.

Yang, G., Dong, J., Chandrasekharan, M.B. and Hall, T.C. 2001. Kiddo, a new transposable element family closely associated with rice genes. Mol. Gen Genet. 266: 417-424.

Li, G., Hall, T. C., and Holmes-Davis, R. 2002. Plant chromatin: development and gene control. Bioessays 24, 234-243.

Chandrasekharan, M.B., Bishop, K.J. and Hall, T.C. 2003. Module- specific expression of the ß-phaseolin promoter during embryogenesis. Plant 33: 853-866.

Chandrasekharan, M.B., Li, G., Bishop, K.J. and Hall, T.C. 2003. S-phase progression is required for PvALF and ABA-mediated transcriptional activation. J. Biol. Chem. 278: 45397-45045.

Grace, M.L., Chandrasekharan, M.B., Hall, T.C. and Crowe, A.J. 2003. Sequence and spacing of TATA box elements are critical for accurate initiation of the ß-phaseolin promoter. J. Biol. Chem. 279: 8102-8110.

Yang, G. and Hall, T.C. 2003. MAK, a computational tool kit for automated MITE analysis. Nucleic Acids Res. 31: 3659-3665.

Yang, G. and Hall, T.C. 2003. MDM-1 and MDM-2: Two Mutator-derived MITE families in rice. J. Mol. Evol. 56: 255B264.

Carranco, R., Chandrasekharan, M.B. Townsend, J.C. and Hall, T.C. 2004. Interaction of PvALF and VP1 B3 domains with the ß-phaseolin promoter. Plant Mol. Biol. Accepted June 2, 2004.

Ng, D. W-K, Chandrasekharan, M.B., Hall, T.C. 2004. The 5' UTR negatively regulates expression from the ABI3 promoter. Plant Mol. Biol. 54: 25-38.

Teerawanichpan, P., Chandrasekharan, M.B., Jiang, Y., Narangajavana, J. and Hall, T.C. 2004. Characterization of two rice DNA methyltransferase genes and RNAi-mediated restoration of promoter activity in silenced rice callus. Planta 218: 337-349.

Zhou, X, Chandrasekharan, M.B., Hall, T.C. 2004. High rooting frequency and functional analysis of GUS and GFP expression in transgenic Medicago truncatula A17. New Phytol. 162: 813-822.