Education and Training
China Agricultural University, China Plant Breeding B.S. 1993
Chinese Academy of Sciences, China Genetics M.S. 1995
Kansas State University, Manhattan, KS Plant Pathology Ph.D. 2003
Harvard Medical School, Boston, MA Molecular Biology Res. Fellow 2003-2009
Research and Professional Experience
2013-present Associate Professor
2009-2013 Assistant Professor, Department of Biochemistry and Biophysics
Institute for Plant Genomics and Biotechnology
Faculty of Molecular & Environmental Plant Sciences (MEPS)
Texas A&M University, College Station, TX
My laboratory is mainly interested in elucidating plant immune signaling pathways by using cellular, functional genomic, genetic and biochemical approaches. Plant immunity is inextricably linked with plant development and environmental stresses. We are also interested in understanding the signaling crosstalk that orchestrates plant responses to different extrinsic and intrinsic signals. Ultimately, knowledge gained from studying model plants, such as Arabidopsis, will be applied to improve crop plants for resistance against different biotic and abiotic stresses.
HONORS AND AWARDS
2008 American Society of Plant Biologists Early Career Award
2002-2003 Don C. Warren Genetic Scholarship, Kansas State University
1998 Second Prize of Natural Science Award, Chinese Academy of Sciences
1998 Special Prize of the President Scholarship, Chinese Academy of Sciences
2012-present Editorial board for Molecular Plant Pathology
2010-present Review editor for Frontier in Plant Physiology
2010-present Member of Department Graduate Recruitment and Admission Committee
2013-present Member of Department Awards committee
2013-2018 NSF-sponsored Green Immunology outreach program
2013 Panel member, USDA-NIFA
SELECTED PEER REVIEWED PUBLICATIONS
- Wu, S., Shan, L., and He, P. (2014) Microbial signature-triggered plant defense responses and early signaling mechanisms. Plant Science http://dx.doi.org/10.1016/j.plantsci.2014.03.001.
- Gao, X., Cox Jr., K.L., and He, P. (2014) Functions of calcium-dependent protein kinases in plant innate immunity. Plants 3:160-176.
- Lin, W., Li, B., Lu, D., Chen, S., Zhu, N., He, P., and Shan L. (2014) Tyrosine phosphorylation of BAK1/BIK1 mediates Arabidopsis innate immunity. Proceedings of the National Academy of Sciences of the United States of America111:3632-3637.
- Zhou, J., Wu, S., Chen, X., Liu, C., Sheen, J., Shan, L., and He, P. (2014) Pseudomonas syringae effector HopF2 suppresses Arabidopsis immunity by targeting BAK1. The Plant Journal 77:235–245.
- Cheng, C, Gao, X, Feng, B, Sheen, J, Shan, L, and He, P. (2013) Plant immune response to pathogens differs with changing temperatures. Nature Communications 4:2530. doi: 10.1038/ncomms3530.
- Lin, W., Lu, D., Gao, X., Jian, S., Ma, X., Wang, Z., Mengiste, T., He, P., and Shan L. (2013) Inverse modulation of plant immunity and plant development by a receptor-like cytoplasmic kinase BIK1. Proceedings of the National Academy of Sciences of the United States of America 110:12114-12119.
- Cui, F., Wu, S., Sun, W., Coaker, G., Kunkel, B. N,, P., and Shan, L. (2013) The Pseudomonas syringae type III effector AvrRpt2 promotes pathogen virulence via stimulating Arabidopsis Auxin/Indole Acetic Acid protein turnover. Plant Physiology 162:1018-1029.
- Gao, X., Chen, X., Lin, W., Lu, D., Niu, Y., Li, L., Cheng, C., McCormack, M., Sheen, J., Shan, L., and He, P. (2013) Bifurcation of Arabidopsis NLR immune signaling via Ca2+-sensor protein kinases. PLoS Pathogens 9, e1003127.
- Lin, W., Ma, X., Shan, L., and He, P. (2013) Big roles of small kinases: the complex functions of receptor-like cytoplasmic kinases in plant immunity and development. Journal of Integrative Plant Biology 55:1188-1197.
- Lu, D., Lin, W., Gao, X., Wu, S., Cheng, C., Avila, J., Heese, A., Devarenne, T., He, P., and Shan, L. (2011) Direct ubiquitination of pattern recognition receptor FLS2 attenuates plant innate immunity. Science 332:1439-1442.
- Gao, X., Wheeler, T., Li, Z., Kenerley, C., He, P., and Shan, L. (2011) Silencing GhNDR1 and GhMKK2 compromised cotton resistance to Verticillium wilt. The Plant Journal 66:293-305.
- Wu, S., Lu, D., Kabbage, M., Wei, H., Swingle, B., Dickman, M., He, P., and Shan, L. (2011) Bacterial effector HopF2 suppresses Arabidopsis innate immunity at the plasma membrane. Molecular Plant-Microbe Interactions 24:585-593.
- Lu, D., Wu, S., Gao, X., Zhang, Y., Shan, L. and He, P. (2010) A receptor-like cytoplasmic kinase BIK1 associates with flagellin receptor complex to initiate plant innate immunity. Proceedings of the National Academy of Sciences of the United States of America 107:496-501.
- Boudsocq, M., Willmann R., McCormack, M., Lee, H., Shan L., He P., Bush, J., Cheng, S., and Sheen J., (2010) Differential innate immune signalling via Ca2+ sensor protein kinases. Nature 464:418-422.
- Chinchilla, D., Shan, L., He, P., de Vries, S. and Kemmerling, B. (2009) One for all-the receptor-associated kinase BAK1. Trend in Plant Science14:535-541.
- Shan, L., He, P., Li, J., Heese, A., Peck, S. C., Nurnberger, T., Martin, G. B., and Sheen, J. (2008) Bacterial effectors target the common signaling partner BAK1 to disrupt multiple MAMP receptor-signaling complexes and impede plant immunity. Cell Host & Microbe 4:17-27.
- Chen, Z., Agnew, J. L., Cohen, J. D., He, P., Shan, L., Sheen, J., and Kunkel, B. N. (2007) Pseudomonas syringae type III effector AvrRpt2 alters Arabidopsis thaliana auxin physiology. Proceedings of the National Academy of Sciences of the United States of America 104:20131-20136.
- Shan, L., He, P., and Sheen, J. (2007) Intercepting host MAPK signaling cascades by bacterial type III effectors. Cell Host & Microbe 1:167-174.
- He, P., Shan, L., and Sheen, J. (2007) Elicitation and suppression of MAMP-triggered immunity in plant-microbe interactions. Cellular Microbiology 9: 1385-1396.
- Sheen, J., and He, P. (2007) Nuclear actions in innate immune signaling. Cell 128:821-823.
- He, P., Shan, L., Lin, N.-C., Martin, G., Kemmerling, B., Nurnberger, T., and Sheen, J. (2006) Specific bacterial suppressors of MAMP signaling upstream of MAPKKK in Arabidopsis innate immunity. Cell 125:563-575.
- He, P., Chintamanani, S., Chen, Z., Zhu, L., Kunkel, B. N., Alfano, J. R., Tang, X., and Zhou, J.-M. (2004) Activation of a COI1-dependent pathway in Arabidopsis by Pseudomonas syringae type III effectors and coronatine. The Plant Journal 37:589-602.
- He, P., Friebe, B. R., Gill, B. S., and Zhou, J.-M. (2003) Allopolyploidy alters gene expression in the highly stable hexaploid wheat. Plant Molecular Biology 52:401-414.